Καινοτομία

The EU-funded project NEUROGENCREB has revealed the critical role of cyclic-AMP Element Binding protein (CREB) in health, neurodegenerative disease, cancer and neural cell survival.

CREB is a phospho-regulated transcription factor. State-of-the-art molecular genetics techniques and bioinformatics showed that CREB has several crucial roles that include neurogenesis, neuronal survival, function, repair and differentiation. CREB acts by modulating gene expression in nerve cells for neuronal activation required in brain functions such as memory and drug addiction.